A close-up of a white bowl filled with shredded, tender Mississippi pot roast, glistening with its own juices.

Mississippi Pot Roast: 5-Ingredient Slow Cooker Magic

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Written by Caroline Hayes

August 22, 2025

I’ll never forget the first time I made Mississippi pot roast—it was pure kitchen magic. My sister, who’s usually the queen of complicated recipes, swore this “dump-and-go” meal was foolproof. I was skeptical—could something so easy really taste that good? Turns out, the answer is a resounding YES. I threw a chuck roast in the slow cooker with ranch seasoning, au jus, butter, and those tangy pepperoncini peppers, then walked away for 8 hours. When I lifted the lid? The most tender, fall-apart beef swimming in the richest, savory juices. My husband took one bite and declared it an instant family favorite. Now it’s our go-to for busy weeknights, lazy Sundays, and even potlucks (where I’m always asked for the recipe). After testing it half a dozen times—adjusting the pepperoncini juice, trying different cuts of meat—I’ve landed on the perfect balance of flavors. Trust me, this hands-off Mississippi pot roast is the kind of meal that’ll make you feel like a kitchen hero without any of the fuss.

Why You’ll Love This Mississippi Pot Roast

This Mississippi pot roast isn’t just good—it’s the kind of meal that’ll make you want to high-five yourself after the first bite. Here’s why it’s earned a permanent spot in our dinner rotation:

  • Dump-and-go magic: Five minutes of prep (no searing required!) and your slow cooker does the rest. Perfect for chaotic weeknights when you’d rather relax than babysit dinner.
  • Flavor bomb: The ranch, au jus, and pepperoncini team up to create this savory, slightly tangy gravy that’ll have you licking the spoon.
  • Budget hero: Chuck roast is affordable, and those pantry-staple seasonings stretch it into a meal that feeds a crowd.
  • Leftover jackpot: The shredded beef gets even better overnight—pile it on sandwiches, toss it with pasta, or layer it onto nachos.
  • Family dinner win: Picky eaters? The mellow heat from the peppers surprises everyone (even kids!) in the best way.

Mississippi Pot Roast Ingredients

This Mississippi pot roast comes together with just 5 simple ingredients—but oh, what magic they make together! Here’s what you’ll need:

  • The star: 3-4 lb chuck roast (go for well-marbled—that fat equals flavor!)
  • The flavor boosters:
    • 1 packet ranch seasoning (I use MSG-free when my sister visits—her stomach thanks me)
    • 1 packet au jus gravy mix (same goes for MSG-free here if you prefer)
  • The richness: 1/2 cup unsalted butter, sliced into pats (trust me, don’t skip this!)
  • The tangy kick:
    • 5-6 pepperoncini peppers (I usually grab the jarred ones)
    • 1/4 cup pepperoncini juice from the jar (this is liquid gold—don’t waste it!)

See why my sister calls this a “kitchen cheat code”? Just toss these pantry staples together and let the slow cooker work its magic.

How to Make Mississippi Pot Roast

This Mississippi pot roast is so easy, you’ll laugh when you see how little effort it takes. The no-sear method means no dirty pans—just layer everything in the slow cooker and let time do the work. Here’s how to make magic happen:

Step 1: Layer the Ingredients

First, plop that beautiful chuck roast right into your slow cooker—no trimming needed, that fat equals flavor! Sprinkle the ranch and au jus packets evenly over the top like you’re seasoning a prized steak. Then, arrange the butter pats across the top (this helps them melt down evenly). Finally, scatter those zippy pepperoncini peppers around the edges and pour the tangy juice right over everything. It’s like building a flavor lasagna!

Step 2: Slow Cook to Perfection

Now, resist the urge to peek! Set your slow cooker to low for 8 hours (my preference—yields ultra-tender shreds) or high for 5-6 hours if you’re short on time. The roast is done when it falls apart with a gentle nudge from a fork. Pro tip: Keep the lid on—every time you lift it, you add 15 minutes to your cook time. When it’s done, shred directly in the pot so the meat drinks up all those glorious juices.

Serving Suggestions for Mississippi Pot Roast

Oh, the places this shredded Mississippi pot roast can go! That rich, tangy juice clinging to the meat doubles as the easiest gravy you’ll ever make. Here’s how we love to serve it:

  • Big ol’ sandwiches: Pile the pepperoncini roast on toasted buns with provolone—the juices soak right in for the messiest (and best) lunch ever.
  • Mashed potato throne: Ladle the beef and its glorious gravy over a mountain of buttery potatoes. Comfort food heaven.
  • Rice bowl magic: Spoon it over jasmine rice with extra pepperoncini juice drizzled on top—it’s like a deconstructed pot roast burrito.
  • Next-day salads: Toss chilled shreds with greens, cherry tomatoes, and a drizzle of the leftover juices for a tangy dressing.

Pro tip: That “au jus” isn’t just for dipping—it’s liquid gold waiting to elevate every bite! Try it with a creamy tomato sauce.

Mississippi Pot Roast Variations

This recipe is so forgiving, you can make it your own with just a few tweaks! Swap in a pork shoulder instead of chuck roast—it shreds just as beautifully. Need to stretch it further? Throw in halved baby potatoes and chunky carrots during the last 3 hours of cooking (they soak up ALL that flavor). Keto friends? Skip the potatoes and serve over creamy cauliflower mash. The possibilities are endless!

Storing and Reheating Leftovers

If you somehow have leftovers (trust me, it’s rare in my house!), here’s how to keep that Mississippi pot roast tasting fresh. Store the shredded beef and juices together in an airtight container—they’ll stay heavenly for up to 3 days in the fridge. My favorite way to reheat? Toss it in a saucepan with a splash of water and warm it gently—those juices reawaken like magic! For the freezer, portion the cooled meat with some gravy in Ziplocs; it keeps beautifully for a month. Just thaw overnight and reheat for a 2-minute comfort food fix.

Mississippi Pot Roast FAQs

I get questions about this Mississippi pot roast all the time—here are the answers to everything you might wonder before making it:

Can I use a different cut of meat?

You absolutely can (I’ve tried them all!), but chuck roast gives the best results. Its marbling melts into the meat, keeping it juicy. If you must swap, go for brisket or pork shoulder—just expect slightly different textures. Leaner cuts like round roast? Not ideal—they’ll dry out.

How can I reduce the sodium?

Easy fixes! First, grab MSG-free ranch and au jus packets—they’re everywhere now. You can also use half the seasoning packets or skip the butter (but honestly, the butter’s worth it). The pepperoncini juice adds salt too, so reduce that if needed.

Can I make it spicier?

Oh yes! Double the pepperoncini peppers AND their juice if you like heat. For serious spice lovers, toss in a few slices of jalapeño or a dash of cayenne with the seasonings. My brother-in-law adds a splash of hot sauce at the end—it’s killer! Try a spicy cucumber salad on the side.

Nutrition Information

Just a heads up—these numbers are estimates since ingredient brands can vary (hello, different ranch seasoning sodium levels!). For one serving of this Mississippi pot roast, you’re looking at about:

  • 450 calories
  • 30g fat (15g saturated from that glorious butter)
  • 40g protein—chuck roast is packed with it!
  • 900mg sodium (use MSG-free packets to lower this if needed)

Pair it with veggies or a salad to balance things out—but honestly? Comfort food this good is worth every bite.

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Mississippi Pot Roast

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A simple slow cooker pot roast with ranch, au jus, and pepperoncini for a flavorful, hands-off meal.

  • Author: Caroline Hayes
  • Prep Time: 10 min
  • Cook Time: 8 hours
  • Total Time: 8 hours 10 min
  • Yield: 6 servings 1x
  • Category: Dinner
  • Method: Slow Cooking
  • Cuisine: American
  • Diet: Low Lactose

Ingredients

Scale
  • 34 lb chuck roast
  • 1 packet ranch seasoning
  • 1 packet au jus gravy mix
  • 1/2 cup unsalted butter
  • 56 pepperoncini peppers
  • 1/4 cup pepperoncini juice

Instructions

  1. Place the chuck roast in the slow cooker.
  2. Sprinkle ranch seasoning and au jus mix over the roast.
  3. Add butter on top.
  4. Place pepperoncini peppers around the roast and pour in the juice.
  5. Cover and cook on low for 8 hours or high for 5-6 hours.
  6. Shred the meat and serve.

Notes

  • Use MSG-free ranch and au jus mixes if preferred.
  • Serve on sandwiches or over mashed potatoes.
  • Store leftovers in an airtight container for up to 3 days.

Nutrition

  • Serving Size: 1 serving
  • Calories: 450
  • Sugar: 2g
  • Sodium: 900mg
  • Fat: 30g
  • Saturated Fat: 15g
  • Unsaturated Fat: 12g
  • Trans Fat: 0g
  • Carbohydrates: 5g
  • Fiber: 1g
  • Protein: 40g
  • Cholesterol: 150mg

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Caroline Hayes is the heart and soul behind Recipes To Keep. Inspired by her grandmother's overflowing recipe box from rural Ohio, Caroline has dedicated herself to preserving timeless American classics. She is a passionate home cook and recipe archivist who specializes in testing and perfecting cherished dishes for the modern kitchen. Her goal is to ensure every recipe is a "keeper"—reliable, delicious, and ready to become a part of your family's story.

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